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Jonah Larkin

When is the best time to take supplements?

By | Origins News, Uncategorized | 6 Comments

At Origins most therapeutic programs involve some sort of supplementation protocol.

We always give our clients a detailed plan of when to take what supplement.

This is important because if you take the wrong supplement at the wrong time it can either negate the benefits of the supplement or cause it to pass through your body without being absorbed.

This just creates really expensive pee!

And the other thing is that each person has different supplement needs at different times due to their activity.

So what supplements should I take when?

For instance when athletes (or anyone for that matter) exercises it creates lots of free radicals (Reactive Oxygen Species-ROS).

In general we want these ROS low as they are implicated in virtually all disease processes from cancer to diabetes.

However, like anything that happens in the body there must be a good reason for it and we have to be careful about manipulating that process.

That good reason is that the body mounts an adaptive response to these ROS especially after exercise.

And in that case we don’t want to blunt the adaptive i.e. muscle building effects of the exercise.

By flooding the body with anti-oxidants during or directly post workout we may blunt the effectiveness of that workout.

So anti-oxidants should be taken as far from a workout as possible.

However other nutrition like amino acids (protein) are best taken within 45 minutes after finishing a workout.

Supplements like Vitamin C and B-Vitamins are water soluble so can be taken anytime.

Others (Vitamins A, D, E and K) are fat soluble and should be taken with meals when we are ingesting some fat.

This increases bio-availability and absorption.

Below is a super basic chart that shows when to take supplements. (Source-Ben Greenfield Fitness)

source: Ben Greenfield Fitness

Be aware that your individual needs may vary depending on your age, your health and fitness goals, the types of activities you do and your fitness levels.

The other thing to be aware of is that the body has a rhythm to it and just like how different hormones are higher at different times of day, the same is true with our vitamin and mineral needs.

This is a great chart that illustrates how timing affects the body and the best time to take your supplements.

What are the supplements that I take personally?

My supplement regimen varies as I can get tired of taking pills.

But…..I generally take the following.

These are supplements and dosages that I take based on lab testing and I do not recommend these for you without a visit with your physician.

Vitamin C: 2000-3000 mg per day.  I have a genetic pre-disposition for Vitamin C deficiency I found through 23andme and the gene calculator from Promethease and Silverberry Genetics.

Vitamin B Complex with methylfolate: I found out I have a genetic variant (MTHFR) that gets in the way of vitamin B methylation so I take the methylated version of this.

Vitamin D with K2: 10000-50000 IU per week depending on the season.  In winter I take more because I’m not out in the sun as much.

Additionally when the sun is at a low angle as it is in winter it we don’t receive intense enough light to create vitamin D in the skin.

Vitamin D should never be taken alone and should always be taken with K2.

This is because Vitamin D moves calcium from the gut into the bloodstream and K2 then directs that calcium into the bones and teeth.

Without the K2 and just the Vitamin D calcium can get deposited in the wrong places like vascular tissue (arteries and veins) as well as the heart.

Magnesium: 400-800 mg generally before bed.

Curcumin: 600-2400 mg per day as an anti-inflammatory.  My preferred brand is Integrative Therapeutics Theracurmin or Metagenics Inflavanoid.

Fish Oil (Omega 3): 3-6 grams per day depending on exercise intensity.

I take Integrative Therapeutics fish oil as you can audit your individual bottle of oil and see exactly what is in it from IT’s excellent lab testing.

Fish oil is one of the supplements that is pretty much a must take these days.

Most people that I have tested are usually deficient in Omega 3 fats and have too many Omega 6 fats.

This results in a pro-inflammatory environment.

Though anecdotal only I have seen many many people get rid of joint and other body pain simply by adding high doses of fish oil to their diet.

Probiotics: Thrive probiotic 1 per day.

There’s lot’s of data about probiotics out there and my takeaway is that anybody who tells you they know what’s going with probiotics is probably full of it.

That doesn’t mean we have not seen benefits from specific strains like S. Boulardi and others.

However Thrive has some great clinical studies behind it for gut lining protection and if you know anything about disease you know that the gut is implicated in most of them.

Collagen Protein: I use Vital Protein’s hydrolyzed beef collagen.

It’s easier to digest than whey protein, has a great amino acid profile including branched chain amino acids.

I use these after a workout or before bed because it helps me sleep better probably due to the high levels of glycine.

Greens: I use Amazing Grass Raw Reserve.

A green powder is like insurance when I’m not getting enough greens, fruits or other vegetables during the day.

Phytonutrients and bioflavanoids are crucial for proper cellular functioning and defense.

Since I exercise frequently I need a ton of anti-oxidants and this is a way to get some through food.

I take other vitamins and minerals less frequently but include

Multi-vitamins: (DFH Twice Daily Essentials) if I’m traveling and I don’t want to carry a ton of pills.

Adaptogenic herbs:  Eleuthero, Rhodiola, Ashwaganda, Shizandra and more.

Anti-oxidants: Resveratrol, CoQ10 and others.

Performance Enhancers: Mitochondrial NRG and others.

Liver Detoxicants: N-Acetyl Cysteine, activated charcoal and other detoxification supplements.

Brain Supplements: High DHA fish oil, Blueberry extract and hesperidin methyl chalcone.

Exogenous Ketones: These are used as meal replacements or to kickstart my body into Ketosis.

Okay I’m sure I’m forgetting some but that covers the basics.

Please let us know below what supplements you take and why and if you have any questions.











Liver Detox Properly-Don’t Make This Simple Mistake

By | Functional Medicine, Origins News, Uncategorized | 2 Comments

Vegies for Liver DetoxOne of the things that drives us absolutely banana’s over here at Origins Medicine is all the horrible advice out there on “cleanses” and “liver detox programs.”

A huge amount of these “cleanses” can often do more harm than good.

When the body releases toxins the liver has to be in tip-top shape in order to eliminate them from the body.

If you’re liver is even a little overburdened then those toxins will simply get recycled right back into the body and not excreted like they should.

This can not only make you sick but increase your risk for degenerative disease.

We run most patients through a two week detox process and make sure to ALWAYS support the liver.

At the bottom of this post there is a link to the detox that we like to use.

Why Should I Detox Anyway?

We live in an incredibly toxic environment.  

It seems to come as surprise to some people that we are part of this polluted environment!

Studies show that the average american has between 300 – 700 toxic chemical contaminants and the average infant is born with 40-70 measurable toxins in their body tissues!

If you don’t eliminate and minimize these toxic loads you are drastically increasing your long term risk of disease.

How Toxins Affect Us

Many of these toxins are endocrine disruptors and neurotoxins, meaning they affect our hormones as well as our brain, nervous system and all the important glands of the body.Organ and Liver Detox

They also cause massive stress on our cells leading to fatigue, premature aging, and create conditions for diseases such as cancer and diabetes.  

When the body is shackled by an undue toxic burden it loses its ability to tolerate even gentle therapeutic supplements.

Solution: Support to Detox the Liver

The liver is a very complicated organ and we are going to make some big oversimplifications.  

Just like cleaning your clothes takes two steps (washing phase and drying phase), the liver goes through two steps as well when it detoxifies. 

Phase 1 is fueled by anti-oxidants to make toxins water soluble and cool inflammation.
Phase 2 Binds these toxins with amino acids so they can be eliminated and excreted.

VegeCleanse Plus Designs for Health

The VegeCleanse Plus provides all the necessary nutrients to make sure the body properly gets rid of toxins.

Imagine trying to wash your clothes with dirty water and no detergent.

It would not work well.

That’s why you need the proper nutrients to help the detox process along.

The Mistake of Most Cleanses and Liver Detox Plans

While the VegeCleanse and other liver supportive cleanses are an ideal way to complete a detox plan there are a bunch of ways that can end up hurting more than they help.

Juice cleanses, fasting without detoxing first and unsupported cleanses like the master cleanse can all be problematic.

When you restrict calories from the body, the body dives into its fat stores to create energy.

Fat is where toxins are stored once the enter the body.

As fat starts to get used these toxins go right back into blood circulation.

Without liver support they simply move to another area in the body.

That’s why people often report feeling sick or ill when they are detoxing.

What most people don’t know is that this is totally un-necessary.

In future blog posts on liver detox and detoxification in general we will dive into the different components to ensure that your cleanse is a success, you lose weight and you feel great!

In the meantime, we would love to know what questions you have.  Please write them in the comments below and we’ll do our best to answer.


The 3 Keys to Naturally Boosting Your Energy

By | Functional Medicine, Origins News | No Comments

There is nothing worse than feeling like your energy is in the tank.

Maybe it’s that 3pm energy dip that only coffee, Redbull, or 4-Hour Energy will cure.

Perhaps you wake up already dreading facing the day.

Or maybe things are generally okay, but you just don’t have the energy to get out, exercise and experience those wonderful feelings of vitality.

You might chalk this up to the fact that you are getting older.

Or, maybe you just feel like you have too much to do and not enough time to get it done. Don’t despair.

There is a proven path to greater energy that thousands like you have already travelled.

Here are 3 options you can follow that will help to dramatically boost your energy and get your life back on track!

  1. Mind your Mitochondria

Mitochondria are the energy engines in each and every cell of your body.

They make fuel called ATP. If they aren’t running well, simply put – your energy is going to suck.

The thing about mitochondria is they require maintenance.

This is both good news and bad news.

The good news is that if properly maintained they last forever! The bad news is that inflammation and nutritional deficiencies break them.

At Origins we have a test that can pinpoint how well your mitochondria are functioning. It also determines whether you’re not producing energy due to inflammation or nutritional problems.

I can’t tell you how many people I’ve seen who have both — inflammation and nutritional deficiencies, which have been ruining their mitochondria.

If you want to make your mito’s work, make sure to supplement properly (we recommend Designs for Health Mitochondrial NRG) and continue reading below.

  1. Hone your hormones

Hormones have a major effect on your energy.

You’ve probably heard of the “stress” hormone cortisol. Cortisol has gotten a bad rap in the press lately.

Of course that’s due to oversimplification and the desire of people to put things in the good vs. bad category.

Cortisol is neither good nor bad, it’s all about how much you have and when you have it.

Cortisol performs a bunch of hyper-critical functions in the body such as decreasing inflammation, regulating the immune response and…wait for it….freeing up blood sugar!

If you’re walking down the street and tiger jumps out in front of you, cortisol gets released to free up blood sugar so you can fight or run.

This is all well and good.

Where people get into trouble is when life situations (like work, finances, relationships etc) lead to a chronic fight or flight response.

When this happens the brain looks all the cortisol pumping around your body and says “hey wait a minute…there’s been too much cortisol running around here for too long.

I better dial this system back so I have it when I need it.”

The brain then down-regulates cortisol production and you start to feel tired.

We run salivary cortisol tests on clients to identify the status of the hormonal system which is a great idea if you think you might be a bit off kilter.

So what’s the solution?

Three things.

Sleep, cutting caffeine and adaptogenic herbs.

Most humans need at least 8 hours of solid sleep. Sleep is how your brain cleanses and resets itself.

Adaptogenic herbs like eleuthero, maca and ashwagandha are also helpful to regulate the overall stress response.

Cutting caffeine so you’re not jacking up your system all the time is also super important.

Some of these “herb” words may sound really different, difficult, or confusing, but it’s actually pretty simple.

At Origins Medicine, we help to identify what is going on and provide, plus explain what each one does and how it works.

That way you begin to feel better and don’t have to search all around town trying to find them and wondering how they work, or how much to take.

If you have insomnia, don’t sleep well, or depend on caffeine and sugar to get you through the day — then be sure to take our test below to see if you have adrenal burnout.

  1. Decrease your Inflammation

You don’t drive your car around with your foot on the brake. Inflammation is the brake that keeps your energy system sub-par.

Inflammation comes from physiological stress on the body and there are three basic types of stress, dietary, inflammatory and emotional.

Dietary Stress

It’s no mystery that the food we eat leads to stress on the body.

What most people don’t know is that many of the foods we eat may appear to be healthy, may actually be processed and have chemicals added to them.

The biggest culprits are sugar and processed foods, refined seed oils (canola, soybean, corn and vegetable), and hormone and antibiotic laden meat and dairy (go organic grass fed here folks).

Oh yeah, non-organic grains like wheat and corn also wreak havoc on your body, as much of it has been washed in fungicides and herbicides. Following an anti-inflammatory diet like the Mediterranean , Paleo or AIP  will do wonders to make you feel better.

Emotional Stress

Constant stress, feeling helpless, unexpressed anger and other emotions all affect our hormones.

Unstable emotions lead to unstable hormones, which lead to unstable emotions.

It’s a big feedback loop!

Emotional stress isn’t going away anytime soon, so it’s critical that we learn how to manage it.

Downtime, play, meditation, counseling/therapy, spiritual practice and getting honest with yourself will help lead you to feeling better, more vital and alive.

Inflammatory Stress

If you have another disease process running in around in your body, it’s important to get some help and therapy with it.

Whether it’s a chronic skin condition, low immune system, or pain that won’t go away — all of these can wreak havoc on other body systems.

This is because chronic inflammation starts to affect other body systems like the mitochondria we discussed above.

Getting these other disease processes managed will help everything else run so very much better.

If you’ve made it this far then you realize that the way we run our energy system has a big effect on how we feel.

Remember that getting your energy back is not an overnight short term project.

I can’t overstate the importance of giving yourself the time and tools to succeed.

If you need support, Origins Medicine is here to help.



Phone: (415) 902-0771